About

James A. Popp

Credentials

• D.V.M., Ph.D.
• Diplomate, American College of Veterinary Pathologists
• Fellow, The Academy of Toxicological Sciences
• Fellow, International Academy of Toxicologic Pathology

Toxicology Experience

• 15 years at CIIT
• Over 10 years in the pharmaceutical industry
• Over 15 years as consultant
• Over 135 publications

Expertise

• Nonclincial safety assessment related to drug development
• Problem resolution in toxicology
• Hepatotoxicity
• Carcinogenicity
• Management of toxicology groups

Offices Held

• Past President, Society of Toxicology
• Past President, The Academy of Toxicological Sciences
• Past President, Society of Toxicologic Pathology
• Past Councilor, American College of Veterinary Pathology

Consulting and Advisory Experience

• Pharmaceutical and chemical companies on specific issues
• Pharmaceutical company program reviews
• Preparation for regulatory agency interactions at all stages of drug development
• Consumer product company advisory panels
• Government review and advisory panels
• International agency review and advisory panels

Selected Publications

• Editor Books
  • Sahota, P.S., Popp, J. A., Hardisty, J.A., Gopinath, C. eds: Toxicologic Pathology: Nonclincial Safety Assessment. 2nd edition CRC Press, Taylor and Francis Group, New York, New York. 2019
• Author Book Chapters
  • Popp, J.A., Englehardt, J.A.: Overview of Drug Development. In: Toxicologic Pathology: Nonclincial Safety Assessment. Sahota, P.S., Popp, J. A., Hardisty, J.A., Gopinath, C. eds. CRC Press, Taylor and Francis Group. Pp.3-26 (2019)
  • Cattley, R.C., Popp, J.A., Vonderfecht S.L.: Liver, Gall Bladder and Exocrine Pancreas. In: Toxicologic Pathology: Nonclincial Safety Assessment. Sahota, P.S., Popp, J. A., Hardisty, J.A., Gopinath, C. eds. CRC Press, Taylor and Francis Group. Pp. 451-513 (2019)
  • Popp J.A., Bogdanffy, M. S.: Evaluation of Potential Carcinogenicity. In: Nonclinical Safety Assessment: A Guide to International Pharmaceutical Regulations. Brock W., Hastings K., McGowan K.M. Eds. John Wiley and Sons, Inc. pp. 219-254 (2013)
• Review article/Position paper
  • Corton J.C., Cunningham M.L., Hummer B.T., Lau C., Meek B., Peters J.M., Popp J.A., Seed J., Klaunig J.E.: Mode of Action Framework Analysis for Receptor-mediated Toxicity: The Peroxisome Proliferator-activated Receptor-alpha (PPARa) as a Case Study. Crit Rev Toxicol 44(1):1-49 (2014)